A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
They published their work today (March 11) in ACS Nano. They also filed a provisional application to patent the technology described in this study.
https://pubs.acs.org/doi/10.1021/acsnano.4c01400
